Super Tadarise Tablet
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What is Super Tadarise Used For?
- Super Tadarise is a dual-action combination tablet by Sunrise Remedies Pvt. Ltd. containing Tadalafil 20mg + Dapoxetine 60mg, prescribed for men with both:
- Erectile Dysfunction – Tadalafil 20mg (the standard maximum on-demand dose) provides the longest coverage window of any approved PDE-5 inhibitor at 36 hours.
- Premature Ejaculation – Dapoxetine 60mg (the maximum approved on-demand PE dose) extends ejaculatory latency within 1–2 hours.
- 36-Hour ED Coverage with On-Demand PE Control – The unique combination of tadalafil's extended window and dapoxetine's on-demand action provides exceptional flexibility across an extended period.
How Does Super Tadarise Work?
- Super Tadarise combines two complementary mechanisms:
- Tadalafil 20mg inhibits PDE-5 with high affinity, sustaining cGMP-mediated penile vasodilation during sexual arousal across the 36-hour pharmacological window.
- Dapoxetine 60mg inhibits serotonin reuptake in the ejaculatory reflex pathway on-demand, extending ejaculatory latency.
- Tadalafil provides extended coverage enabling multiple encounters; dapoxetine provides control for each individual encounter.
How to Use Super Tadarise
Dosage: One tablet 30–120 minutes before sexual activity.
Timing: Tadalafil onset 30–120 min, 36-hour window. Dapoxetine peaks 1–2 hours.
Precaution: One tablet per 24 hours. Contraindicated with nitrates and serotonergic drugs.
Side Effects of Super Tadarise
Common: Back pain, myalgia, nausea, headache, dizziness, flushing, dry mouth.
Serious (seek medical help): Severe hypotension, serotonin syndrome, priapism, syncope.
Drug Interactions — Important Information
| Drug / Substance | Interaction Type | Risk Level | Action Required |
|---|---|---|---|
| Nitrates (any form) | Severe hypotension — prolonged risk due to 36-hr tadalafil half-life | 🔴 Absolute Contraindication | Do NOT combine — risk of fatal BP drop |
| MAOIs (phenelzine, tranylcypromine, selegiline) | Serotonin syndrome (dapoxetine component) | 🔴 Absolute Contraindication | Do NOT combine; 14-day washout required after stopping MAOIs |
| Thioridazine / Linezolid | Serotonin syndrome (dapoxetine component) | 🔴 Contraindicated | Do NOT combine |
| Other PDE-5 inhibitors | Additive PDE-5 vasodilation | 🔴 Contraindicated | Never combine two PDE-5 inhibitors |
| SSRIs / SNRIs (fluoxetine, paroxetine) | Serotonin syndrome + elevated dapoxetine via CYP2D6 inhibition | 🟠 Serious | Avoid; physician monitoring required |
| Alpha-blockers (tamsulosin, doxazosin) | Additive hypotension | 🟠 Serious | Start at lowest dose; physician supervision |
| Ritonavir / CYP3A4 inhibitors | Increases tadalafil and dapoxetine exposure | 🟠 Serious | Maximum 10 mg tadalafil per 72 hrs; dose reduction required |
| Alcohol (heavy use) | Additive vasodilation + CNS depression | 🟡 Moderate | Avoid alcohol with this combination |
Always inform your doctor about all medications, supplements, and recreational substances you are taking before starting this medication. This list is not exhaustive.
Frequently Asked Questions
Q1: What is Super Tadarise?
Super Tadarise is a combination tablet by Sunrise Remedies Pvt. Ltd. containing Tadalafil 20mg and Dapoxetine 60mg. It simultaneously treats erectile dysfunction with 36-hour tadalafil coverage and premature ejaculation with on-demand dapoxetine control in a single tablet.
Q2: Why combine tadalafil's 36-hour window with dapoxetine's short-acting PE control?
Tadalafil 20mg provides extended erectile readiness across a 36-hour window — enabling multiple encounters without re-dosing. Dapoxetine 60mg provides on-demand ejaculatory control for each individual encounter within that window. The combination offers the maximum flexibility of any dual ED+PE tablet.
Q3: How is Super Tadarise different from Tadapox?
Super Tadarise and Tadapox both contain Tadalafil 20mg + Dapoxetine 60mg. They are different brand names from Sunrise Remedies for the same pharmacological combination. Clinical efficacy and safety are identical.
Q4: How quickly does Super Tadarise work?
Tadalafil 20mg onset is 30 to 120 minutes with sexual stimulation. Dapoxetine peaks at 1–2 hours. Unlike sildenafil, tadalafil absorption is not significantly affected by food, allowing Super Tadarise to be taken at any time relative to meals.
Q5: Can Super Tadarise be taken with food?
Yes. Tadalafil absorption is food-independent. Dapoxetine has minor food-related absorption differences without clinical significance. Super Tadarise can be taken with or without food — an advantage over sildenafil-based combinations.
Q6: What are the side effects of Super Tadarise?
Tadalafil 20mg contributes back pain and myalgia (from PDE-11 inhibition), flushing, headache, and nasal congestion. Dapoxetine 60mg contributes nausea, dizziness, and dry mouth. The combined profile requires physician assessment of tolerability for the individual patient.
Q7: What drugs are contraindicated with Super Tadarise?
Nitrates and riociguat are absolutely contraindicated with tadalafil. MAOIs and all serotonergic drugs — SSRIs, SNRIs, triptans, tramadol, linezolid, lithium, St John's wort — are contraindicated with dapoxetine. Alpha-blockers require careful evaluation due to additive hypotension.
Q8: Can alcohol be taken with Super Tadarise?
Alcohol must be avoided. Dapoxetine 60mg significantly amplifies alcohol's CNS depressant effects. Tadalafil adds further blood pressure-lowering. The combination with even moderate alcohol creates substantial syncope risk.
Q9: Does Super Tadarise cause back pain?
Yes. Back pain and myalgia are the characteristic side effects of tadalafil, distinct from other PDE-5 inhibitors. These typically appear 12–24 hours after dosing and resolve spontaneously. They are more prominent with tadalafil than with sildenafil, vardenafil, or avanafil.
Q10: Is Super Tadarise suitable for spontaneous sexual activity?
Yes. Tadalafil's 36-hour window allows more spontaneous use than sildenafil's 4–6 hour window. Once the tablet is taken and onset achieved, there is no time pressure within the extended window. This makes Super Tadarise well-suited to couples with less predictable timing.
Q11: How does Super Tadarise compare to Super P-Force?
Super Tadarise provides 36-hour erectile window with standard dapoxetine; Super P-Force provides 4–6 hour window. Both use Dapoxetine 60mg. Super Tadarise suits men wanting extended spontaneous coverage; Super P-Force suits men who prefer sildenafil or shorter activity windows.
Q12: Is a prescription required for Super Tadarise?
Yes. Both tadalafil and dapoxetine are prescription-only medicines. A physician must evaluate cardiovascular fitness, screen for serotonergic drug interactions, and confirm that both ED and PE are co-existing conditions before prescribing Super Tadarise.
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Clinical References
This product information is supported by peer-reviewed clinical evidence:
- Brock GB, et al. (2002). Efficacy and safety of tadalafil for the treatment of erectile dysfunction: results of integrated analyses. Journal of Urology, 168(4), 1332–1336. [PubMed: 12352386]
- Pryor JL, et al. (2006). Efficacy and tolerability of dapoxetine in treatment of premature ejaculation: an integrated analysis of two double-blind, randomised controlled trials. Lancet, 368(9539), 929–937. [PubMed: 16962882]
- Burnett AL, et al. (2018). Erectile Dysfunction: AUA Guideline. Journal of Urology, 200(3), 633–641. [PubMed: 29746858]
- Hatzimouratidis K, et al. (2010). EAU Guidelines on Male Sexual Dysfunction. European Urology, 57(5), 804–814. [PubMed: 20189712]
Disclaimer
The information provided on Medionix Pharma is intended for general informational purposes only. It should not be considered as medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional before using any medication or starting any treatment.
Medionix Pharma does not encourage self-medication. Customers are responsible for ensuring that purchases comply with local laws and prescription requirements in their country. If you have any questions or concerns regarding the content on our website, please contact us at sales@medionixpharma.com.