Extra Super Tadarise Tablet
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What is Extra Super Tadarise Used For?
- Extra Super Tadarise is a high-strength dual-action tablet by Sunrise Remedies Pvt. Ltd. containing Tadalafil 40mg + Dapoxetine 60mg, prescribed for men with co-existing:
- Severe Erectile Dysfunction – Tadalafil 40mg is above the standard maximum on-demand dose (20mg), providing intensified PDE-5 inhibition with 36-hour coverage for refractory ED.
- Premature Ejaculation – Dapoxetine 60mg (maximum approved PE dose) extends ejaculatory latency through serotonin reuptake inhibition.
- Above-Guideline Tadalafil Dose – For men who have not achieved adequate ED response at standard tadalafil 20mg, requiring step-up therapy under physician supervision.
How Does Extra Super Tadarise Work?
- Extra Super Tadarise delivers two complementary mechanisms:
- Tadalafil 40mg provides double the standard maximum on-demand dose — achieving higher plasma concentrations, stronger PDE-5 inhibition, and more pronounced penile vasodilation across tadalafil's characteristic 36-hour activity window.
- Dapoxetine 60mg inhibits serotonin reuptake in the ejaculatory reflex pathway, extending ejaculatory latency and improving control.
How to Use Extra Super Tadarise
Dosage: One tablet 30–120 minutes before sexual activity, with or without food.
Timing: Tadalafil 40mg: onset 30–120 min, 36-hour window. Dapoxetine peaks 1–2 hours.
Precaution: One tablet per 24 hours. Contraindicated with nitrates and serotonergic drugs.
Side Effects of Extra Super Tadarise
Common: Pronounced back pain and myalgia, nausea, headache, dizziness, flushing.
Serious (seek medical help): Severe hypotension, serotonin syndrome, priapism, syncope.
Extra Dosage Comparison Guide
| Strength | Best For | Onset | Duration | Link |
|---|---|---|---|---|
| 40 mg + 60 mg | Lower strength option | 30–120 min | Up to 36 hrs | View → |
| 100 mg / 100 mg | Popular strength option | 30–120 min | Up to 36 hrs | View → |
| 200 mg / 60 mg | Maximum strength variant | 30–120 min | Up to 36 hrs | View → |
* Always consult your doctor before changing your dosage. This information is for educational reference only.
Drug Interactions — Important Information
| Drug / Substance | Interaction Type | Risk Level | Action Required |
|---|---|---|---|
| Nitrates (any form) | Severe hypotension — prolonged risk due to 36-hr tadalafil half-life | 🔴 Absolute Contraindication | Do NOT combine — risk of fatal BP drop |
| MAOIs (phenelzine, tranylcypromine, selegiline) | Serotonin syndrome (dapoxetine component) | 🔴 Absolute Contraindication | Do NOT combine; 14-day washout required after stopping MAOIs |
| Thioridazine / Linezolid | Serotonin syndrome (dapoxetine component) | 🔴 Contraindicated | Do NOT combine |
| Other PDE-5 inhibitors | Additive PDE-5 vasodilation | 🔴 Contraindicated | Never combine two PDE-5 inhibitors |
| SSRIs / SNRIs (fluoxetine, paroxetine) | Serotonin syndrome + elevated dapoxetine via CYP2D6 inhibition | 🟠 Serious | Avoid; physician monitoring required |
| Alpha-blockers (tamsulosin, doxazosin) | Additive hypotension | 🟠 Serious | Start at lowest dose; physician supervision |
| Ritonavir / CYP3A4 inhibitors | Increases tadalafil and dapoxetine exposure | 🟠 Serious | Maximum 10 mg tadalafil per 72 hrs; dose reduction required |
| Alcohol (heavy use) | Additive vasodilation + CNS depression | 🟡 Moderate | Avoid alcohol with this combination |
Always inform your doctor about all medications, supplements, and recreational substances you are taking before starting this medication. This list is not exhaustive.
Frequently Asked Questions
Q1: What is Extra Super Tadarise?
Extra Super Tadarise is a combination tablet by Sunrise Remedies Pvt. Ltd. containing Tadalafil 40mg and Dapoxetine 60mg. The above-guideline tadalafil dose (standard max is 20mg) with maximum dapoxetine is prescribed for men with both severe refractory erectile dysfunction and premature ejaculation.
Q2: Why does Extra Super Tadarise use Tadalafil 40mg when the standard is 20mg?
Tadalafil 40mg provides double the standard maximum on-demand dose, achieving higher plasma concentrations and stronger PDE-5 inhibition for men with refractory ED who have not responded adequately to standard tadalafil 20mg. This above-guideline dose is used under specialist supervision only.
Q3: How long does Extra Super Tadarise remain active?
Tadalafil 40mg maintains the same 36-hour pharmacological activity window as standard tadalafil, but at higher plasma concentrations throughout. Dapoxetine 60mg peaks at 1–2 hours and clears within 24 hours, providing ejaculatory control for the immediate encounter.
Q4: What are the most prominent side effects of Extra Super Tadarise?
Back pain and myalgia from tadalafil's PDE-11 inhibition are substantially more pronounced at 40mg than at 20mg. Nausea, dizziness, and dry mouth from dapoxetine add to the side effect burden. Headache, flushing, and significant blood pressure lowering are also expected.
Q5: Can Extra Super Tadarise be taken with food?
Yes. Tadalafil absorption is food-independent. Dapoxetine has minor food interaction effects without clinical significance. Extra Super Tadarise can be taken with or without food, unlike sildenafil-based combinations which require food avoidance for optimal absorption.
Q6: What drugs are contraindicated with Extra Super Tadarise?
Organic nitrates and riociguat are absolutely contraindicated with tadalafil. All serotonergic drugs — MAOIs, SSRIs, SNRIs, triptans, tramadol, linezolid, and St John's wort — are contraindicated with dapoxetine. Alpha-blockers require careful physician evaluation given the additive hypotensive risk at 40mg tadalafil.
Q7: Is Tadalafil 40mg safe to use?
Tadalafil 40mg is used in specific above-guideline clinical contexts under specialist supervision. Safety requires full cardiovascular assessment, confirmation of adequate response failure at 20mg, absence of nitrate or severe cardiovascular contraindications, and ongoing medical monitoring.
Q8: How does Extra Super Tadarise compare to Tadapox?
Both contain Tadalafil + Dapoxetine. Tadapox uses standard Tadalafil 20mg + Dapoxetine 60mg. Extra Super Tadarise doubles the tadalafil dose to 40mg for refractory ED — it is a step-up from Tadapox when 20mg/60mg is well-tolerated but provides insufficient erection response.
Q9: Can alcohol be taken with Extra Super Tadarise?
Alcohol must be avoided. Dapoxetine significantly amplifies alcohol's central nervous system and cardiovascular effects. Combined with above-standard tadalafil's blood pressure-lowering effect at 40mg, alcohol creates substantial syncope and hypotension risk.
Q10: Is Extra Super Tadarise suitable for first-time combination therapy?
No. Extra Super Tadarise contains above-guideline tadalafil 40mg and is not a first-line treatment. First-line combination therapy would be Tadapox (Tadalafil 20mg + Dapoxetine 60mg). Extra Super Tadarise is for men with documented inadequate response to standard doses.
Q11: Does Extra Super Tadarise cause serotonin syndrome?
Yes, if combined with serotonergic drugs. Dapoxetine 60mg co-administered with any other serotonergic agent can trigger serotonin syndrome — a potentially life-threatening condition. Disclosure of all medications to the prescribing physician is mandatory.
Q12: Is a prescription required for Extra Super Tadarise?
Yes, and specialist oversight is recommended. The above-guideline tadalafil 40mg dose and the dual combination with dapoxetine require documented failure at standard doses and physician confirmation of cardiovascular safety before prescribing Extra Super Tadarise.
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Customer Reviews
Ryan M.
Germany · 1 month ago
“Shipped to Germany within 12 days. Arrived in a plain padded envelope. Tablet is genuine and effective.”
Tom C.
USA · 2 months ago
“Tried several online suppliers — Medionix is the only one where I was 100% confident in product authenticity.”
Paul D.
USA · 3 months ago
“The product quality is pharmaceutical-grade. Packaging was professionally sealed. No signs of tampering on arrival.”
Marcus L.
UK · 2 weeks ago
“Reliable supplier. Tablets came in sealed blister packs with clear batch number and expiry date visible. Highly effective.”
Chris W.
USA · 6 weeks ago
“First order from Medionix — impressed. Product is authentic, packaging was sealed, delivery was faster than expected.”
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Clinical References
This product information is supported by peer-reviewed clinical evidence:
- Brock GB, et al. (2002). Efficacy and safety of tadalafil for the treatment of erectile dysfunction: results of integrated analyses. Journal of Urology, 168(4), 1332–1336. [PubMed: 12352386]
- Pryor JL, et al. (2006). Efficacy and tolerability of dapoxetine in treatment of premature ejaculation: an integrated analysis of two double-blind, randomised controlled trials. Lancet, 368(9539), 929–937. [PubMed: 16962882]
- Burnett AL, et al. (2018). Erectile Dysfunction: AUA Guideline. Journal of Urology, 200(3), 633–641. [PubMed: 29746858]
- Hatzimouratidis K, et al. (2010). EAU Guidelines on Male Sexual Dysfunction. European Urology, 57(5), 804–814. [PubMed: 20189712]
Disclaimer
The information provided on Medionix Pharma is intended for general informational purposes only. It should not be considered as medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional before using any medication or starting any treatment.
Medionix Pharma does not encourage self-medication. Customers are responsible for ensuring that purchases comply with local laws and prescription requirements in their country. If you have any questions or concerns regarding the content on our website, please contact us at sales@medionixpharma.com.