O-Stat 60mg Capsule — Orlistat 60mg view 1
    O-Stat 60mg Capsule — Orlistat 60mg view 2
    O-Stat 60mg Capsule — Orlistat 60mg view 3

    O-Stat 60mg Capsule

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    🩺Medically reviewed by Dr. Priya Sharma, PharmD, BCCP · Last reviewed: June 2025
    Generic:OrlistatFormat:Strip of 10 CapsulesStrength:60mgManufacturer:Sun Pharmaceutical IndustriesCategory:Weight Loss MedicinesAvailability:In Stock

    O-Stat 60mg Capsule

    contains Orlistat 60mg, a gastrointestinal lipase inhibitor used for weight management in overweight adults when combined with a mildly hypocaloric, lower-fat diet. At the 60mg dose (taken three times daily), orlistat blocks approximately 25% of dietary fat absorption in the intestine, helping create a caloric deficit that supports gradual weight loss.

    Benefits:

    - Blocks approximately 25% of dietary fat from being absorbed in the gut

    - Supports gradual, sustainable weight loss of 5–10% of body weight over 6 months

    - Reduces the absorption of fat-soluble calories without systemic drug effects

    - Lower 60mg dose with a reduced side-effect profile compared to 120mg

    - Can be purchased over-the-counter in many markets at this dose level

    How It Works:

    Orlistat irreversibly inhibits gastric and pancreatic lipases in the lumen of the small intestine, preventing the hydrolysis of dietary triglycerides into absorbable fatty acids and monoacylglycerols. Undigested fat passes through the intestine and is excreted in the faeces. This selective reduction in dietary fat absorption creates a daily caloric deficit, contributing to progressive weight loss when combined with a reduced-fat, reduced-calorie diet.

    Dosage and Administration:

    Take one 60mg capsule three times daily with each main meal containing fat, either during or up to 1 hour after the meal. If a meal is missed or contains no fat, the dose for that meal may be skipped. The capsule is taken orally with water.

    Side Effects:

    Common and dose-related (reduced with a low-fat diet): oily spotting on underwear, fatty or oily stools, oily discharge, increased defecation urgency, faecal incontinence, flatulence with oily discharge. Uncommon: abdominal pain or discomfort. Rare: severe liver injury (discontinue and seek medical attention if jaundice, dark urine, or abdominal pain develops).

    Precautions:

    Take a daily multivitamin containing fat-soluble vitamins (A, D, E, K) at least 2 hours before or after orlistat doses, as absorption may be reduced. Not suitable for patients with chronic malabsorption syndrome, cholestasis, or known hypersensitivity to orlistat. Not recommended during pregnancy or breastfeeding.

    O-stat Dosage Comparison Guide

    StrengthBest ForOnsetDurationLink
    60mgLower strength option30–60 minPer mealCurrent
    120mgMaximum strength variant30–60 minPer mealView →

    * Always consult your doctor before changing your dosage. This information is for educational reference only.

    Frequently Asked Questions

    Q1: What is O-Stat 60mg used for?

    O-Stat 60mg contains orlistat, a fat-blocking agent used to support weight loss in overweight adults alongside a reduced-calorie, lower-fat diet. At 60mg three times daily, it blocks approximately 25% of dietary fat absorption.

    Q2: How does O-Stat 60mg differ from O-Stat 120mg?

    O-Stat 60mg contains half the dose of orlistat compared to 120mg. The 60mg dose is suitable for overweight adults seeking weight management support, while 120mg is a prescription dose for more significant obesity requiring stronger fat-blocking effect.

    Q3: Does O-Stat 60mg cause oily stools?

    Yes. Oily, fatty stools are the most common and expected side effect of orlistat. They occur because unabsorbed fat passes through the intestine. Eating a low-fat diet (under 30% of calories from fat per meal) significantly reduces this effect.

    Q4: Can I take O-Stat 60mg without changing my diet?

    Orlistat works best — and causes fewer GI side effects — when combined with a reduced-fat diet. Taking it without dietary changes will not produce meaningful weight loss and will cause more severe oily stools and urgency.

    Q5: Does O-Stat 60mg affect vitamin absorption?

    Yes. Orlistat reduces absorption of fat-soluble vitamins A, D, E, and K. Take a daily multivitamin containing these vitamins at bedtime or at least 2 hours away from your orlistat dose to ensure adequate vitamin levels.

    Q6: How much weight will I lose on O-Stat 60mg?

    Clinical studies show that adults on orlistat 60mg with dietary changes lose approximately 3–5 kg more over 6 months compared to diet alone. Results depend on adherence to a low-fat diet and caloric restriction.

    Q7: Can O-Stat 60mg be taken long-term?

    Orlistat at 60mg is generally safe for up to 6 months of continuous use. Longer-term use should be reviewed by a healthcare provider. The prescription 120mg version has been studied for up to 4 years of use.

    Q8: Is O-Stat 60mg suitable for people with diabetes?

    Orlistat can be used in patients with type 2 diabetes; in fact, it may improve glycaemic control by reducing caloric intake. Blood glucose monitoring should be intensified, as antidiabetic drug doses may need adjustment.

    Q9: Can I take O-Stat 60mg with thyroid medication?

    There is a potential interaction between orlistat and levothyroxine due to reduced absorption of thyroid hormone. Take levothyroxine at least 4 hours away from orlistat doses, and monitor thyroid function closely.

    Q10: Does O-Stat 60mg work if I eat a very low-fat meal?

    If a meal contains little or no fat, orlistat has minimal effect — there is no fat to block. You may skip the orlistat dose for that meal, as taking it without dietary fat confers no benefit and wastes the capsule.

    Customer Reviews

    Dr. Maria Santos

    Australia · 3 weeks ago

    “Good quality product. Shipping was fast and handled with care. Would recommend for professional hospital procurement.”

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    Michael K.

    USA · 2 months ago

    “Fast international shipping and professional packaging. Product was exactly as described. Highly recommend this supplier.”

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    Dr. James Wilson

    USA · 1 week ago

    “Excellent product quality. Arrived well-packaged with proper cold chain maintained throughout transit. Will order again.”

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    Priya Sharma

    India · 1 month ago

    “Prompt response from the team and smooth ordering process. Medicine arrived in original sealed packaging as expected.”

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    FirstCare Clinic

    Canada · 3 months ago

    “Good value for bulk procurement orders. Communication was clear and the shipment arrived within the estimated timeframe.”

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    Disclaimer

    The information provided on Medionix Pharma is intended for general informational purposes only. It should not be considered as medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional before using any medication or starting any treatment.

    Medionix Pharma does not encourage self-medication. Customers are responsible for ensuring that purchases comply with local laws and prescription requirements in their country. If you have any questions or concerns regarding the content on our website, please contact us at sales@medionixpharma.com.

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