Glycoheal G 502 SR Tablets-Glycoheal G502 Tablets

Q1: What is Glycoheal G 502 SR used for?

Glycoheal G 502 SR (Glimepiride 2mg + Metformin 500mg SR) is used for type 2 diabetes requiring dual-mechanism control with the convenience of once-daily dosing and better tolerability from the sustained-release Metformin component.

Q2: How does Glycoheal G 502 SR work?

Glimepiride 2mg closes ATP-sensitive potassium channels on beta cells, triggering insulin release. Metformin SR 500mg activates AMPK pathways to reduce liver glucose output and enhance muscle glucose uptake, with steady release minimizing GI effects.

Q3: When should I take Glycoheal G 502 SR?

Take once daily with breakfast or dinner as directed by your physician. Consistent meal timing is important for both efficacy and hypoglycemia prevention.

Q4: Why is the sustained-release formulation beneficial?

Metformin SR 500mg reduces the nausea and diarrhea associated with the higher peak levels of immediate-release Metformin, improving patient adherence to long-term therapy.

Q5: Can Glycoheal G 502 SR cause low blood sugar?

Yes. Glimepiride 2mg stimulates insulin release regardless of blood glucose level and can cause hypoglycemia, particularly if a meal is skipped or delayed. Always have fast-acting glucose available.

Q6: What are the most common side effects?

Common side effects include hypoglycemia, nausea, diarrhea, flatulence, and headache. The SR formulation reduces GI effects compared to immediate-release alternatives.

Q7: Can I crush or split the G 502 SR tablet?

No. Do not crush, chew, or break sustained-release tablets — this destroys the SR mechanism and can cause a sudden large Metformin dose release. Swallow whole.

Q8: Is Glycoheal G 502 SR safe for kidney disease?

Not recommended when eGFR is below 30 ml/min. Regular kidney function monitoring every 6–12 months is needed during long-term use.

Q9: Can I take this during pregnancy?

No. Both Glimepiride and Metformin are contraindicated during pregnancy. Insulin is the preferred treatment. Report any pregnancy to your doctor immediately.

Q10: What precautions apply before surgery or contrast imaging?

Hold Metformin 48 hours before iodinated contrast procedures or major surgery. Resume only after renal function has been confirmed normal.

Q11: How often should I check blood sugar?

Regular home monitoring is important, especially when starting or adjusting doses. HbA1c every 3 months; kidney function tests annually or more often if at risk.

Q12: Do I need a prescription?

Yes, a prescription is required. Your doctor will review kidney function, meal regularity, and current diabetes control before prescribing this once-daily SR combination.