Dapagliflozin Tablet 10mg
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What is Dapagliflozin 10mg Used For?
- Dapagliflozin 10mg is used for:
- Type 2 Diabetes Management – Helps lower blood sugar levels in adults with type 2 diabetes
- Heart Failure Treatment – Reduces the risk of cardiovascular death and hospitalization in patients with heart failure
- Chronic Kidney Disease – Slows progression of kidney disease in diabetic patients
How Does Dapagliflozin Work?
- Dapagliflozin contains Dapagliflozin, an SGLT-2 inhibitor which:
- Blocks glucose reabsorption in the kidneys, allowing excess sugar to be excreted in urine
- Reduces blood glucose levels without stimulating insulin release
- Provides cardiovascular and renal protective benefits independent of blood sugar control
How to Use Dapagliflozin 10mg
Dosage: Take one 10mg tablet once daily
Timing: Can be taken with or without food, preferably in the morning
Precaution: Stay well hydrated; monitor for signs of urinary tract infections or genital fungal infections
Side Effects of Dapagliflozin
Common Side Effects: Increased urination, genital yeast infections, urinary tract infections, thirst
Serious Side Effects (seek medical help): Ketoacidosis (nausea, vomiting, abdominal pain, confusion), severe dehydration, Fournier's gangrene (rare genital infection)
Benefits
- Lowers HbA1c by 0.5–1.0% as monotherapy or add-on therapy
- Promotes modest weight loss (1–3 kg) through urinary glucose excretion
- Reduces systolic blood pressure by 2–4 mmHg independent of diuretics
- Demonstrated cardiovascular mortality reduction in the DECLARE-TIMI trial
- Slows progression of chronic kidney disease in diabetic and non-diabetic patients
- Low intrinsic hypoglycemia risk as it does not stimulate insulin secretion
Warnings and Precautions
- Risk of diabetic ketoacidosis (DKA) — can occur even with near-normal blood glucose; stop if DKA suspected
- Genital mycotic infections are more frequent; maintain good hygiene
- Rare but serious risk of Fournier's gangrene — seek immediate care for perineal pain, swelling, or fever
- Volume depletion may occur; use caution in elderly patients or those on diuretics
- Hold before any surgical procedure or iodinated contrast imaging
- Not recommended if eGFR is below 25 ml/min/1.73m²
Drug Interactions
- Diuretics: increased risk of dehydration and hypotension
- Insulin or sulfonylureas: increased hypoglycemia risk; dose reduction may be needed
- Lithium: SGLT2 inhibitors may reduce lithium levels; monitor closely
- NSAIDs: combined use may increase risk of acute kidney injury
Storage Information
- Store at room temperature between 15–25°C
- Keep in the original blister pack to protect from moisture
- Do not store in the bathroom or near heat sources
Frequently Asked Questions
Q1: What is Dapagliflozin used for?
Dapagliflozin is an SGLT-2 inhibitor used to control blood sugar in type 2 diabetes, reduce heart failure risk, and protect kidney function.
Q2: How does Dapagliflozin lower blood sugar?
It blocks the SGLT-2 transporter in the kidneys, preventing glucose reabsorption and allowing excess sugar to be excreted in urine — a process independent of insulin.
Q3: When is the best time to take Dapagliflozin?
Take once daily, preferably in the morning, with or without food. Morning dosing helps avoid increased nighttime urination.
Q4: What is the usual starting dose?
The standard dose is 10mg once daily. Your doctor will assess kidney function (eGFR) before and periodically during treatment.
Q5: Can Dapagliflozin cause low blood sugar?
Dapagliflozin alone rarely causes hypoglycemia. Risk increases when combined with insulin or sulfonylureas — your doctor may reduce those doses.
Q6: Can I take Dapagliflozin with food?
Yes, it can be taken with or without food. Consistent daily timing is more important than meal timing.
Q7: What are the most common side effects?
Increased urination, genital yeast infections, urinary tract infections, and thirst are most common. Good hygiene and adequate hydration help manage these.
Q8: Is Dapagliflozin safe for people with kidney disease?
It requires dose review based on eGFR. Not recommended when eGFR is below 25 ml/min. In early CKD, it actually helps protect the kidneys.
Q9: Can I take Dapagliflozin during pregnancy?
No. Dapagliflozin is not recommended during pregnancy, especially in the second and third trimesters. Use effective contraception and inform your doctor if planning to conceive.
Q10: How often should I check my blood sugar while on Dapagliflozin?
Regular home monitoring is recommended. HbA1c should be checked every 3 months. Your doctor will guide frequency based on your full regimen.
Q11: How should I store Dapagliflozin?
Store between 15–25°C in the original blister pack, away from moisture and heat. Do not refrigerate or freeze.
Q12: Do I need a prescription for Dapagliflozin?
Yes, Dapagliflozin is a prescription-only medicine. A doctor must evaluate kidney function, cardiovascular status, and other medications before prescribing.
Customer Reviews
Helen B.
UK · 2 weeks ago
“Dapagliflozin tablets are genuine. Packaging shows manufacturer details, lot number, and expiry. Reordering next month.”
Betty L.
USA · 6 weeks ago
“Managing diabetes requires consistent medication supply. Medionix has been fully dependable for 8 months of regular orders.”
Carol P.
Australia · 3 months ago
“Good service and genuine product. Glimepiride tablets came exactly as described. Delivery was prompt and packaging secure.”
Helen B.
UK · 2 weeks ago
“Dapagliflozin tablets are genuine. Packaging shows manufacturer details, lot number, and expiry. Reordering next month.”
Betty L.
USA · 6 weeks ago
“Managing diabetes requires consistent medication supply. Medionix has been fully dependable for 8 months of regular orders.”
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The information provided on Medionix Pharma is intended for general informational purposes only. It should not be considered as medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional before using any medication or starting any treatment.
Medionix Pharma does not encourage self-medication. Customers are responsible for ensuring that purchases comply with local laws and prescription requirements in their country. If you have any questions or concerns regarding the content on our website, please contact us at sales@medionixpharma.com.