Poxet 90mg Tablet
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What is Poxet 90mg Used For?
- Poxet 90mg is the maximum-dose Dapoxetine tablet by Sunrise Remedies, prescribed for:
- Moderate to Severe Premature Ejaculation – For men who did not achieve sufficient ejaculatory control with the 30mg dose.
- Extended IELT Improvement – Provides greater increase in intravaginal ejaculation latency time compared to lower doses.
- Step-Up PE Therapy – Used after confirming tolerability at 30mg and clinical need for stronger effect.
How Does Poxet 90mg Work?
- At 90mg, Dapoxetine provides:
- Maximum serotonin reuptake inhibition in ejaculatory control centres of the central nervous system.
- Significant delay in the ejaculatory reflex arc, extending voluntary control over ejaculation timing.
- Rapid pharmacokinetic profile retained — still suitable for on-demand use before sexual activity.
- No effect on erectile function; acts selectively on ejaculation pathways.
How to Use Poxet 90mg
Dosage: One 90mg tablet taken with a full glass of water, 1–3 hours before sexual activity.
Timing: Take while sitting or lying down to minimise syncope risk. Effects last approximately 1–3 hours.
Precaution: Do not exceed one tablet per 24 hours. Strictly avoid alcohol, SSRIs, MAOIs, SNRIs. Only use after confirming tolerability at the 30mg dose.
Side Effects of Poxet 90mg
Common Side Effects: Nausea, dizziness, headache, diarrhoea, dry mouth, insomnia, fatigue — generally more pronounced than at 30mg.
Serious Side Effects (seek medical help): Syncope, serotonin syndrome, severe orthostatic hypotension, mania, allergic reactions.
Poxet Dosage Comparison Guide
| Strength | Best For | Onset | Duration | Link |
|---|---|---|---|---|
| 30 mg | Lower strength option | 1–2 hrs | 4–6 hrs | View → |
| 90 mg | Maximum strength variant | 1–2 hrs | 4–6 hrs | Current |
* Always consult your doctor before changing your dosage. This information is for educational reference only.
Drug Interactions — Important Information
| Drug / Substance | Interaction Type | Risk Level | Action Required |
|---|---|---|---|
| MAOIs (phenelzine, tranylcypromine, selegiline) | Serotonin syndrome — potentially fatal | 🔴 Absolute Contraindication | Do NOT combine; 14-day washout required after stopping MAOIs |
| Thioridazine | Serotonin syndrome | 🔴 Absolute Contraindication | Do NOT combine |
| Linezolid / IV methylene blue | Serotonin toxicity | 🔴 Contraindicated | Do NOT combine |
| SSRIs / SNRIs (fluoxetine, paroxetine, venlafaxine) | Serotonin syndrome; CYP2D6 inhibition raises dapoxetine levels | 🟠 Serious | Avoid co-use; physician supervision essential |
| Tramadol / opioids | Additive serotonin effect | 🟠 Serious | Avoid combination |
| Alcohol / CNS depressants | Enhanced CNS depression; increased syncope risk | 🟡 Moderate | Avoid alcohol before and after dose |
Always inform your doctor about all medications, supplements, and recreational substances you are taking before starting this medication. This list is not exhaustive.
Frequently Asked Questions
Q1: What is Poxet 90mg used for?
Poxet 90mg contains Dapoxetine 90mg, the maximum clinical dose for premature ejaculation. It is prescribed for men who achieved insufficient ejaculatory control at the 30mg dose and need stronger serotonergic activity.
Q2: Is 90mg the maximum dose of dapoxetine?
Yes. 90mg is the maximum approved dose of dapoxetine for premature ejaculation. Doses higher than this are not clinically recommended and carry disproportionate side effect risk.
Q3: How much more effective is Poxet 90mg than 30mg?
Clinical studies show dapoxetine 60mg increases IELT by approximately 3 times placebo, and 90mg may provide further benefit in non-responders to lower doses, though individual response varies considerably.
Q4: When should I take Poxet 90mg?
Take Poxet 90mg 1 to 3 hours before planned sexual activity. Swallow whole with a full glass of water. Sit or lie down for a period after ingestion to reduce dizziness risk.
Q5: What side effects are more common with Poxet 90mg than 30mg?
All side effects of dapoxetine — nausea, headache, dizziness, diarrhoea — are more pronounced at 90mg compared to 30mg. The risk of syncope and orthostatic hypotension is also significantly elevated.
Q6: Can Poxet 90mg cause serotonin syndrome?
Yes. If combined with other serotonergic drugs (SSRIs, SNRIs, MAOIs, lithium, tramadol, triptans), dapoxetine 90mg can precipitate serotonin syndrome — a serious condition with agitation, fever, rapid heart rate, and potential seizures.
Q7: Who must not take Poxet 90mg?
Men taking MAOIs, SSRIs, SNRIs, thioridazine, or lithium; those with cardiac failure, arrhythmia, or fainting history; those with hepatic impairment; and those who have not previously tolerated dapoxetine 30mg must not use this dose.
Q8: Can Poxet 90mg be combined with ED medications?
Poxet 90mg can be combined with PDE-5 inhibitors under physician guidance, but this combination requires careful blood pressure monitoring given the additive hypotensive effects.
Q9: Is Poxet 90mg safe for long-term use?
Dapoxetine is approved for on-demand use rather than long-term daily therapy. Long-term outcomes at 90mg specifically have not been as extensively studied. Regular medical review is recommended.
Q10: Can I drive after taking Poxet 90mg?
Driving is not recommended for several hours after taking Poxet 90mg, as dizziness, syncope, and reduced concentration are possible. Allow time to assess your individual response before driving.
Q11: What should I do if I faint after taking Poxet 90mg?
If syncope occurs, lie flat, raise your legs, and call for medical help. Inform your doctor about the episode. They may recommend dose reduction to 30mg or discontinuation of dapoxetine.
Q12: Do I need a prescription for Poxet 90mg?
Yes. Dapoxetine 90mg requires a valid prescription. A physician should confirm the PE diagnosis, ensure no contraindicated medications are taken, and confirm cardiovascular safety before prescribing.
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Clinical References
This product information is supported by peer-reviewed clinical evidence:
- Pryor JL, et al. (2006). Efficacy and tolerability of dapoxetine in treatment of premature ejaculation: an integrated analysis of two double-blind, randomised controlled trials. Lancet, 368(9539), 929–937. [PubMed: 16962882]
- McMahon CG, et al. (2008). An evidence-based definition of lifelong premature ejaculation: report of the International Society for Sexual Medicine Ad Hoc Committee for the Definition of Premature Ejaculation. BJU International, 102(3), 338–350. [PubMed: 18498422]
- Hatzimouratidis K, et al. (2010). EAU Guidelines on Male Sexual Dysfunction. European Urology, 57(5), 804–814. [PubMed: 20189712]
Disclaimer
The information provided on Medionix Pharma is intended for general informational purposes only. It should not be considered as medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional before using any medication or starting any treatment.
Medionix Pharma does not encourage self-medication. Customers are responsible for ensuring that purchases comply with local laws and prescription requirements in their country. If you have any questions or concerns regarding the content on our website, please contact us at sales@medionixpharma.com.