
Intacoxia Etoricoxib 90mg Tablet
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What is Etoricoxib Used For?
- Etoricoxib is used for:
- Cancer Pain Management β Adjunct therapy for pain control in oncology patients
- Bone Metastases Pain β Relief of pain from skeletal involvement
- Post-Surgical Pain β After cancer-related surgical procedures
- Inflammatory Pain β When inflammation contributes to cancer-related discomfort
How Does Etoricoxib Work?
- Etoricoxib is a selective COX-2 inhibitor, which:
- Selectively blocks cyclooxygenase-2 (COX-2) enzyme
- Reduces prostaglandin synthesis at sites of inflammation
- Provides anti-inflammatory and analgesic effects with reduced GI side effects compared to traditional NSAIDs
How to Use Etoricoxib
Dosage: 60-90mg once daily depending on pain severity
Administration: Take orally with or without food
Precaution: Use lowest effective dose for shortest duration; monitor cardiovascular and renal function; physician supervision required
Side Effects of Etoricoxib
Common Side Effects: Headache, dizziness, hypertension, GI discomfort, peripheral edema
Serious Side Effects (seek medical help): Cardiovascular events (heart attack, stroke), GI bleeding, severe skin reactions, liver damage
Benefits
- Selective COX-2 inhibitor β analgesic and anti-inflammatory with lower GI ulcer risk than non-selective NSAIDs
- Once-daily dosing simplifies pain management in outpatient oncology care
- Useful for bone metastases pain where prostaglandins contribute to osteolytic pain signaling
- Non-opioid option that can reduce opioid requirements when used as part of multimodal pain management
- Effective for post-operative inflammatory pain after cancer surgeries
Warnings and Precautions
- Cardiovascular risk: increases risk of heart attack and stroke β use lowest effective dose for shortest duration; contraindicated in established ischaemic heart disease or stroke history
- GI bleeding: lower risk than non-selective NSAIDs but not eliminated β use with caution in patients on anticoagulants
- Hypertension: can raise blood pressure β monitor regularly; dose adjustment of antihypertensives may be needed
- Renal impairment: reduce dose or avoid in eGFR <30 ml/min
- Contraindicated in uncontrolled hypertension, severe heart failure, severe liver disease, active peptic ulcer
- Not for use in pregnancy (third trimester) β causes premature ductus arteriosus closure
Drug Interactions
- Warfarin and anticoagulants: COX-2 inhibitors potentiate anticoagulant effect β monitor INR closely when starting or adjusting dose
- ACE inhibitors, ARBs, diuretics: combination may reduce antihypertensive effect and increase renal impairment risk
- Non-selective NSAIDs: increased GI toxicity risk β avoid concurrent use
- Ciclosporin and tacrolimus: NSAIDs increase nephrotoxicity risk of calcineurin inhibitors
Storage Information
- Store at room temperature 15Β°Cβ30Β°C, protected from moisture
- Keep in original blister packaging, out of reach of children
- Do not use after expiry date
Frequently Asked Questions
Q1: What is Etoricoxib 90mg used for in cancer care?
Etoricoxib is a selective COX-2 inhibitor used as supportive analgesic therapy in oncology patients for bone metastases pain, post-surgical discomfort after cancer procedures, and inflammatory pain components of cancer-related conditions.
Q2: How does Etoricoxib relieve pain?
Etoricoxib selectively inhibits the COX-2 enzyme, reducing prostaglandin synthesis specifically at sites of inflammation and pain. This provides anti-inflammatory and analgesic effects with fewer gastric side effects compared to non-selective NSAIDs.
Q3: How is Etoricoxib 90mg administered?
Take 90mg once daily orally, with or without food. For acute pain, 90mg is the typical dose. Use the lowest effective dose for the shortest duration necessary.
Q4: Can I take Etoricoxib long-term for cancer pain?
Etoricoxib should be used at the lowest effective dose for the shortest required period. Long-term use increases cardiovascular and renal risk. Your doctor will reassess the need for continued treatment regularly.
Q5: What are the most common side effects?
Common side effects include headache, dizziness, high blood pressure, peripheral edema, and gastrointestinal discomfort. Unlike older NSAIDs, Etoricoxib has lower risk of GI ulcers.
Q6: What serious side effects require emergency care?
Seek immediate care for: chest pain or stroke symptoms (cardiovascular events), severe abdominal pain or black stools (GI bleeding), significantly reduced urine output (renal failure), or severe skin reactions.
Q7: Can Etoricoxib be used alongside cancer chemotherapy?
This requires careful evaluation by your oncologist. Some chemotherapy agents affect renal function, which may increase Etoricoxib's renal toxicity risk. Regular renal function monitoring is essential during concurrent use.
Q8: Is Etoricoxib safe for patients with high blood pressure?
Etoricoxib can raise blood pressure. Blood pressure must be monitored during treatment, and antihypertensive medications may need adjustment. It is contraindicated in uncontrolled hypertension.
Q9: Does Etoricoxib interact with warfarin or blood thinners?
Yes. Etoricoxib can potentiate anticoagulant effects of warfarin. INR should be monitored closely when starting or changing the dose. Inform your prescriber of all anticoagulant medications.
Q10: Who should not take Etoricoxib?
Etoricoxib is contraindicated in patients with active peptic ulcers, severe heart failure, severe renal impairment (eGFR <30), severe liver disease, uncontrolled hypertension, or known cardiovascular disease at high risk.
Q11: Can Etoricoxib be taken during cancer treatment?
Yes, it is commonly used as adjunct analgesia during cancer treatment. However, the treating oncologist must review all medications for interactions and ensure renal/hepatic function is adequate before prescribing.
Q12: Is a prescription required for Etoricoxib 90mg?
Yes. Etoricoxib requires a prescription. Its cardiovascular and renal risks mean it should only be used under medical supervision with appropriate monitoring.
Customer Reviews
Regional Cancer Institute
USA Β· 6 weeks ago
βUsed Medionix for supplementary oncology supply for over a year now. Reliable, consistent quality and timely delivery.β
Dr. Fatima Al-Rashid
UK Β· 3 months ago
βTrusted source for specialist oncology procurement. Products always arrive within expiry in manufacturer-sealed packaging.β
Northside Medical Center
Australia Β· 3 weeks ago
βRoutine oncology supply order. Medications arrived temperature-controlled and within the stated delivery window. Highly reliable.β
Regional Cancer Institute
USA Β· 6 weeks ago
βUsed Medionix for supplementary oncology supply for over a year now. Reliable, consistent quality and timely delivery.β
Dr. Fatima Al-Rashid
UK Β· 3 months ago
βTrusted source for specialist oncology procurement. Products always arrive within expiry in manufacturer-sealed packaging.β
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The information provided on Medionix Pharma is intended for general informational purposes only. It should not be considered as medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional before using any medication or starting any treatment.
Medionix Pharma does not encourage self-medication. Customers are responsible for ensuring that purchases comply with local laws and prescription requirements in their country. If you have any questions or concerns regarding the content on our website, please contact us at sales@medionixpharma.com.





