Acutret Isotretinoin 20mg Capsules

Q1: What is Acutret 20mg (Isotretinoin 20mg) used for?

Acutret 20mg treats moderate to severe cystic and nodular acne in patients for whom a 20mg daily dose is appropriate (typically 40–60kg patients at 0.5 mg/kg/day, or larger patients at lower dose intensity). It is manufactured by Ipca Laboratories.

Q2: How does Acutret 20mg work?

Isotretinoin reduces sebaceous gland size and activity by up to 90%, normalizes follicular keratinization, reduces Cutibacterium acnes colonization, and has direct anti-inflammatory effects — providing comprehensive acne control that often leads to permanent remission.

Q3: When will Acutret 20mg start working?

Most patients notice some improvement after 6–8 weeks, though an initial acne flare (temporary worsening) is common in the first 4–6 weeks. Full results become evident after completing the entire treatment course.

Q4: What is the teratogenicity requirement for Acutret 20mg?

Isotretinoin causes severe birth defects at all doses. Women of childbearing potential must use TWO effective methods of contraception throughout treatment and for 1 month after the final dose. Monthly pregnancy tests are mandatory during treatment.

Q5: What are the most common side effects at 20mg?

Dry lips (cheilitis), dry skin, nosebleeds, dry eyes, joint pain, and an initial acne flare are most common. These are more pronounced than at 10mg. Intense lip care and skin moisturisation significantly reduces discomfort.

Q6: What blood monitoring is required during Acutret 20mg?

Liver function tests (ALT, AST) and fasting lipid panel (triglycerides, cholesterol) at baseline and monthly during treatment. Monthly pregnancy tests for females. Any significant abnormality may require dose reduction or treatment suspension.

Q7: Can I use topical acne treatments with Acutret 20mg?

Avoid topical retinoids (tretinoin, adapalene) as they cause excessive irritation. Benzoyl peroxide and salicylic acid should generally be avoided. Use only gentle, hydrating cleansers and moisturisers during treatment.

Q8: Is sun protection important during Acutret 20mg treatment?

Yes. Isotretinoin increases photosensitivity. Apply SPF 30+ broad-spectrum sunscreen daily, wear protective clothing, and avoid prolonged sun exposure and tanning beds throughout treatment.

Q9: Can I donate blood while on Acutret 20mg?

No. Blood donation is prohibited during treatment and for 1 month after the last dose, as donated blood could harm a pregnant recipient who might receive it.

Q10: What happens if I miss a dose of Acutret 20mg?

Take the missed dose as soon as you remember on the same day. If you remember the next day, skip the missed dose and continue your regular schedule. Do not double up. Contact your dermatologist if you miss multiple doses.

Q11: How should Acutret 20mg capsules be stored?

Store at room temperature (15°C–30°C) away from light and moisture. Keep capsules in original blister packs until use.

Q12: Do I need a prescription for Acutret 20mg?

Yes. Isotretinoin at 20mg requires a dermatologist prescription with mandatory pregnancy prevention and monthly blood test monitoring.